Birth Defects
About 3% of all babies born in the U.S. are affected by birth defects. Birth defects are structural changes in the baby that may or may not be compatible with life. These changes can be mild or severe and can affect a single part or multiple parts of the body. Some defects can be treated with surgical and other medical interventions. Diagnosis usually occurs within the first year of a baby’s life. Some defects can be diagnosed during pregnancy through screening and other types of tests.

Birth defects are thought to be a result of a combination of factors, including:
- Genetic
- Behavioral
- Environmental
In other words, a defect may be a result of several factors working together. For most birth defects, causes are complex and not well understood. We do know that a developing fetus as well as infants and children face special risks from environmental exposures because their bodies are small and still developing.
The connections between environmental exposures and birth defects are not fully clear. We know a lot of exposure to certain chemicals could increase the risk of defects. These chemicals include polychlorinated biphenyls (PCBs), dioxins, pesticides, and others. Exposure to high levels of radiation may also increase defect risk.
How can pregnant women be exposed to pollutants of concern?
- Eating contaminated fish
- Breathing contaminated air in the workplace or at home
- Drinking water from contaminated wells
- Smoking
In most cases, a birth defect is not caused by anything a parent did or didn’t do, but there are a few actions that can be taken:
- Avoid smoking and second-hand smoke
- Stop use of illicit drugs
- Talk to your healthcare provider about concerns related to environmental exposures at work or at home
The Virginia EPHT program collects data trends on twelve conditions. These defects were selected because of their possible link with environmental risk factors. They include:
- Anencephaly
- Cleft Lip with Cleft Palate
- Cleft Lip without Cleft Palate
- Cleft Palate without Cleft Lip
- Gastroschisis
- Hypoplastic Left Heart Syndrome
- Hypospadias
- Limb Deficiencies
- Spina Bifida
- Tetralogy of Fallot
- Transposition of the Great Arteries (Vessels)
- Trisomy 21
Click here to see the data in a visualization dashboard.
Helpful Links
- See vdh.virginia.gov/vacares/birth-defects/ to learn more about birth defects and newborn screening in VA
- See birth defects dashboard
- See cdc.gov/birth-defects/ to view more on birth defects from CDC

Contact Us
Virginia Environmental Public Health Tracking Program
Virginia Department of Health
P.O. Box 2448
Richmond, Virginia 23218-2448
109 Governor Street
Richmond, Virginia 23219