Treatment Guidance

The STOMP Trial is recruiting patients to learn if tecovirimat (TPOXX) is a safe and effective treatment for human mpox virus. Patients do not have to have severe mpox or be at risk of severe mpox to enroll in the STOMP Trial. Click here for more information. 

There is currently no treatment approved specifically for mpox virus infections. However, antivirals developed for use in patients with smallpox may prove beneficial against mpox. CDC provides Mpox Treatment Information for Healthcare Professionals and Interim Clinical Treatment Considerations for Severe Manifestations of Mpox. 

Individuals with immunocompromising conditions may require early and prolonged treatment. See CDC’s Clinical Considerations for Treatment and Prophylaxis of Mpox Infection in People Who are Immunocompromised. 

A VDH “Mpox Overview for Healthcare Providers” webinar recorded on October 21, 2022 is also available as a resource for clinicians. 

Page Last Updated: January 25, 2024

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