MPox – Administering Jynneos Smallpox Vaccine

-- Please note that JYNNEOS is a subcutaneously administered vaccine.  It is NOT meant to be delivered into the muscle.
-- JYNNEOS is administered as two subcutaneous injections 28 days apart.
-- JYNNEOS is a two dose vaccine series.  The immune response to JYNNEOS takes 14 days after the second dose for maximal development.
-- JYNNEOS contains a live Vaccinia virus that does not replicate efficiently in human cells.
-- On August 9, 2022, the FDA issued an Emergency Use Authorization (EUA) for the JYNNEOS vaccine to allow healthcare providers to use the vaccine by intradermal injection for individuals 18 years of age and older who are determined to be at high risk for monkeypox infection.

VDH: Monkeypox - Administering JYNNEOS Vaccine Intradermally Train-the-Trainer

TRAIN Course ID: 1105479

Length: 2 hours

Description: This training will familiarize participants with how to administer the JYNNEOS vaccine intradermally.

Target Audience: Licensed Clinicians (i.e., registered nurse, nurse practitioner, physician assistant, and/or physician).

Training Handouts
-- JYNNEOS Vaccine Administration Training Checklist
-- JYNNEOS Intradermal Vaccine Administration Job Aid
-- Monkeypox JYNNEOS Standing Orders Alt Dose
-- Monkeypox JYNNEOS Standing Orders Standard


Learning Objectives:
(1) Introduce the JYNNEOS vaccination
(2) Describe and prepare JYNNEOS vaccine
(3) Practice administering the JYNNEOS vaccine intradermally on an injection pad
(4) Be evaluated on conducting a hands-on practice of administering JYNNEOS vaccine intradermally on an injection pad

This webpage is current as of: September 16, 2022.